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Evaluation of coronary atherosclerosis on T1WI for preventing future events registry (secondary prevention)

Evaluation of coronary atherosclerosis on T1WI for preventing future events registry (secondary prevention) - T1WI CAD 2nd prevention registry

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000029246
Enrollment
300
Registered
2017-09-22
Start date
2017-05-30
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischemic heart disease

Interventions

None listed

Sponsors

Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients with (A) stable coronary artery disease (B) unstable angina (C) acute myocardial infarction (Type 1 by 3rd universal definition) without indication of primary PCI, who has intermediate stenosis at proximal segment of each coronary vessels (segments #1, #2, #3, #5, #6, #7, #11, or #13) detected on coronary computed tomography angiography (CCTA) or invasive coronary angiography (CAG) and undergo coronary magnetic resonance for plaque evaluation by T1WI within 3 months before/after anatomical evaluation by CCTA, CAG evaluation or both.

Exclusion criteria

Exclusion criteria: Patients with MRI contraindication Patients with chronic kidney disease (stage 4 and 5) or with hemodialysis Patients with pacemaker, implantable cardiodefibrillatior Patients with heart rhythm irregularity (Atrial fibrillation etc) Patients with claustrophobia Patients judged as inappropriate by each researcher

Design outcomes

Primary

MeasureTime frame
Composite of major adverse event (cardiac death, myocardial infarction (3rd universal definition: type1), new ischemia driven coronary revascularization)

Secondary

MeasureTime frame
All-cause death Cardiac death Cardiovascular death Myocardial infarction/unstable angina New ischemia driven coronary revascularization Occurrence of periprocedural myocardial injury during percutaneous coronary intervention (PCI) (3rd Universal definition type 4). Slow flow phenomenon during PCI.

Countries

Japan

Contacts

Public ContactYasuhide Yasuhide Asaumi

National Cerebral and Cardiovascular Center Department of Cardiovascular Medicine

asaumiya@ncvc.go.jp06-6170-1070

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026