Lower Rectal Cancer
Conditions
Interventions
Transanal and transperineal total prostatectomy with total mesorectal excision
Sponsors
Saku Central Hospital Advanced Care Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) The patients with the lower rectal cancer which invades the only middle part of the seminal vesicles or the prostate. 2) The patients who agreed the entry of this study of their own free will in writing by a principal or a substitute after they had comprehended it well by enough explanation.
Exclusion criteria
Exclusion criteria: 1) The patients with the lower rectal cancer which had widespread invasion of the seminal vesicles, the prostate, the pelvic nerve, the urinary bladder, and the urethra are excluded. 2) The patients who underwent neoadjuvant CRT in particular more than 45 Gry are e excluded because of much risk of leakage of the anastomotic site between the urinary bladder and the urethra. 3) When the proper surgical field or further improvement in manipulation cannot be obtained during TaTMEP or TpTMEP, the approach method should be changed into other approaches such as laparoscopy or open laparotomy, or other surgical methods such as transanal or transperineal total pelvic exenteration. 4) The patients who are inappropriate as the subjects of this study by the corresponding doctor are excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Surgical bleeding, surgical time, circumferential resected margin of the surgical specimen, leakage at the anastomotic site between the bladder and the urethra, post-surgical urinary function regarding voiding and continence | — |
Secondary
| Measure | Time frame |
|---|---|
| Post-surgical complications including urinary tract infection, pelvic abscess, paresis of intestine, and leakage at the coloanal anastomotic site post sphincter preserving surgery, closure rate of covering ileostoma, 3-year local recurrence rate, 3-year overall survival rate, and 3-year disease-free survival. | — |
Countries
Japan
Contacts
Public ContactMiyuki Niimi
Saku Central Hospital Advanced Care Center Clinical Research Center
Outcome results
None listed