The study of the relationship between oxygen dose at night and arterial partial pressure of carbon dioxide in type 2 chronic respiratory failure patients

The study of the relationship between oxygen dose at night and arterial partial pressure of carbon dioxide in type 2 chronic respiratory failure patients - The relationship between oxygen dose at night and arterial partial pressure of carbon dioxide

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000029222

Enrollment

Registered

2017-09-20

Start date

2017-01-11

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with chronic hypercapnic respiratory failure receiving a long-term oxygen therapy and noninvasive positive pressure ventilation (NPPV)

Interventions

Low dose oxygen, one night (one week) Middle dose oxygen, one night (one week) High dose oxygen, one night Low dose oxygen, one night (one week) High dose oxygen, one night (one week) Middle d

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients receiving long-term oxygen therapy and long-term NPPV with chronic respiratory failure. Underling disease do not matter (COPD, Interstitial pneumoniae, Nontuberculous mycobacteriosis, Bronchiectasis, etc.)

Exclusion criteria

Exclusion criteria: Clinically unstable

Design outcomes

Primary

Measure	Time frame
The relationship between oxygen dose and some parameters (sleep structure, PtcCO2 at night, and SpO2 at night)	—

Secondary

Measure	Time frame
The relationship between oxygen dose and some parameters (respiratory status, sleepiness, sympathetic nerve activity, cardiovascular load, and pulmonary function)	—

Countries

Japan

Contacts

Public ContactKensuke Sumi

National Hospital Organization Minami-Kyoto Hospital Department of Respiratory Medicine

kensukesumi@gmail.com0774-52-0065

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026