Herpes zoster neuralgia
Conditions
Interventions
Methylprednisolone80mg + 0.1%ropivacaine + sufentanil100ug+0.9%NaCl=400ml, continuous epidural injection for 8day
Methylprednisolone80mg + 0.1%ropivacaine + sufentanil100ug+ketamine100mg+0.9%NaCl=400m
Sponsors
Department of Anesthesiology, General Hospital of Tianjin Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1 older than 50 years inpatient, younger than 90 years inpatient 2 dermatome below C6 3 Moderate to serve pain(NRS baseline mort than 6 )persisting for more than 3 months after onset of herpes zoster rash 4 Uncontrollable pain by conventional drugs 5 Normal cognitive and communicative ability and ability to complete self-report questionnaires
Exclusion criteria
Exclusion criteria: 1 patients with facial involvement 2 known sensitivity to methylprednisolone, ketamine,ropivacaine, and sufentanil 3 serious mental or psychiatric illness 4 Drug addiction and alcoholism 5 Bacterial infection of the skin overlying the vertebra of the affected dermatome 6 bronchial asthma, serve hypertension, serious cardiovascular disease, serve hepatic and renal dysfunction, serious hematological disease 7 patients participated in other clinical study in recent 6 months 8 Non-compliant patient who will not complete relative treatment and questionnaires. 9 Patients with any unsuitable situation decided by researchers will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the offect of pain variation effect different drugs on herpes zoster neuralgia (PHN) | — |
Countries
Asia(except Japan)
Contacts
Public ContactHongguang Chen
Department of Anesthesiology, General Hospital of Tianjin Medical University General Hospital of Tianjin Medical University
Outcome results
None listed