Borderline hyper LDL cholesterolemia
Conditions
Interventions
A green tea beverage was given twice a day at mealtimes for 8 weeks.
Sponsors
Central Research Institute, ITO EN, Ltd.
Orthomedico Inc.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Subjects judged to be appropriate by the responsible physician 2) Subjects have a higher LDL- cholesterol in screening test (the responsible physician may exclude subjects with extremely low cholesterol absorption markers )
Exclusion criteria
Exclusion criteria: 1) A history of malignant tumor, heart failure, or myocardial infarct 2) Currently under the treatment for either cardiac arrhythmia, hepatic disorder, renal disorder, cerebrovascular disorder, rheumatism, diabetes mellitus, dyslipidemia or hypertension 3) Subjects use or take "Foods for Specified Health Uses" and "Foods with Functional Claims" in daily 4) Currently taking medicines and/or herbal medicine 5) Those who are allergic to medicines and/or the test food related products 6) Pregnant, subjects with lactation period, or subjects having the mind to become pregnant in the test period 7) Subjects who participated in other clinical tests in 3 months before writing informed consent of this study was obtained 8) Subjects who are inadequate for enrollment judged by the responsible physician
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cholesterol synthesis and absorption markers(0, 4, and 8 wk) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Synthesis/absorption(0, 4, and 8 wk) 2) LDL-cholesterol(0, 4, and 8 wk) 3) HDL-cholesterol(0, 4, and 8 wk) 4) Total cholesterol(0, 4, and 8 wk) 5) LDL/HDL(0, 4, and 8 wk) 6) Correlation between changing rate of LDL-cholesterol and changing rate of each of cholesterol absorption and synthesis markers from baseline to 8 weeks | — |
Countries
Japan
Contacts
Public ContactMakoto Kobayashi, PhD
ITO EN, Ltd. Central Research Institute
Outcome results
None listed