Healthy volunteer
Conditions
Interventions
Placebo period (9 days) - washout period - SNR15 period (9 days)
SNR15 period (9 days) - washout period - Placebo period (9 days)
Sponsors
TES Holdings Co.,Ltd
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Subjects who can make self-judgment and are voluntarily giving written informed consent. 2)Healthy males aged between 30 and 64. Healthy post-menopausal females aged between 50 and 64 with no menstruation in the past 12 months. 3)Subjects whose urinary sodium excretion in screening examination is low. 4)Subjects who routinely not take medicine, supplements, FOSHU, and/or health food which affect to the result of the study.
Exclusion criteria
Exclusion criteria: 1)Subjects who have allergy to medicinal and foods. 2)Subjects who has under treatment or a history of serious disease (e.g., diabetes, liver disease, kidney disease, or heart disease). 3)Subjects whose systolic blood pressure is more than 140 mmHg or diastolic blood pressure is more than 90 mmHg. 4)Subjects whose BMI is more than 30 kg/m2. 5)Subjects who make a blood donation of 400 ml within 12 weeks before the start of the intake or that of 200 ml within 4 weeks before the start of the intake. 6)Subjects who are estimated inappropriate to participate to this study by principal investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Urinary electrolyte | — |
Secondary
| Measure | Time frame |
|---|---|
| Plasma concentration of SNR15 metabolite | — |
Countries
Japan
Contacts
Public ContactRyoma Shimizu
TES Holdings Co.,Ltd Clinical research
Outcome results
None listed