Skip to content

A prospective randomized controlled trial of isotonic versus hypotonic maintenance intraveneous fluids after surgery for children

A prospective randomized controlled trial of isotonic versus hypotonic maintenance intraveneous fluids after surgery for children - A prospective randomized controlled trial of isotonic versus hypotonic maintenance intraveneous fluids after surgery for children

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000029057
Enrollment
100
Registered
2017-11-01
Start date
2018-01-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pediatric patient who will be performed abdominal surgery.

Interventions

Extracellular fluid is used as a postoperative maintenance intraveneous fluidsuntil 3 days after operation. Half saline is used as a postoperative maintenance intraveneous fluidsuntil 3 days after ope

Sponsors

Nagoya University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients who are undergoing surgery in our department and are expected to have meals on or after the 3rd postoperative day.

Exclusion criteria

Exclusion criteria: Patients suffering from heart disease, renal disease, central nervous disease, patients taking diuretics, neonates.

Design outcomes

Primary

MeasureTime frame
Blood sampling are performed on the 3rd postoperative day. Primary outcome is serum Na, 136 mEq / L or less is defined as hyponatremia and its frequency is compared.

Secondary

MeasureTime frame
Secondary endpoints were examination of changes in serum Na levels before and after surgery and analyzed ADH, plasma osmotic pressure, urinary osmotic pressure and urinary Na, respectively, and compared with SIADH and also consider the relationship.

Countries

Japan

Contacts

Public ContactKazuki Kazuki

Nagoya University Graduate School of Medicine Pediaric surgery

k-yokota@med.nagoya-u.ac.jp052-744-2959

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026