Effect of exercise therapy with tibial internal-rotation on clinical outcomes and knee kinematics of osteoarthritis of the knee: a randomized controlled trial

Effect of exercise therapy with tibial internal-rotation on clinical outcomes and knee kinematics of osteoarthritis of the knee: a randomized controlled trial - Effect of exercise therapy with tibial internal-rotation

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000029045

Enrollment

Registered

2017-09-29

Start date

2016-01-27

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis of the knee

Interventions

Novel knee exercise therapy with tibial internal-rotation was carried out for 3 months (once a week). Intervention was a manual therapy for improving range of tibial internal-rotation, and 3 exercises

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Japanese males and females, 2) between 50 and 80 years old, 3) primary medial compartment knee osteoarthritis, 4) radiographic severity classified using Kellgren-Lawrence classification grade was grade I to grade III.

Exclusion criteria

Exclusion criteria: 1) Lateral compartment knee osteoarthritis, 2) history of knee surgery, 3) receiving some kind of rehabilitation program, 4) subject who has a serious disease on knee joint, 5) history of rheumatoid arthritis, cerebropathy, neuropathy, gout, 6) risk of internal medicine, 7) mental disorder, 8) communication disorder

Design outcomes

Primary

Measure	Time frame
Knee joint kinematics before and after intervention (3 months)	—

Secondary

Measure	Time frame
Knee flexion/extension angle, Timed Up & Go Test, 20 m gait, WOMAC, SF-36, MRI, parameters of gait (three-dimensional analysis)	—

Countries

Japan

Contacts

Public ContactYasuo Kurose

Hiroshima Prefectural Rehabilitation Center Department of Orthopaedics

kurose0156@hiroshima-wsc.jp082-425-1455

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026