Study of the efficacy and safety of Java ginger(Bangle, Zingiber purpureum) against cognitive decline in the elderly

Study of the efficacy and safety of Java ginger(Bangle, Zingiber purpureum) against cognitive decline in the elderly - Study of the efficacy and safety of Java ginger(Bangle, Zingiber purpureum) against cognitive decline in the elderly

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000029027

Enrollment

Registered

2017-09-11

Start date

2017-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mild Cognitive Impairment

Interventions

Examination period: 24 weeks from the consent acquisition, 24 weeks observation period after the end of the dose, for a total of 48 weeks Test food: 3 tablets twice daily (tablets containing 85 mg of

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Subjects were those who were diagnosed with mild cognitive impairment (MCI) among those who received Dementia-Related Disease Medical Center in the Kochi Medical School Hospital.

Exclusion criteria

Exclusion criteria: 1. Persons suffering from dementia 2. Serious heart disease, liver disease, kidney disease, blood disease, lung disease, and those suffering from diseases judged to affect life 3. Persons who can not orally administer 4. Others who are deemed inappropriate by the research doctor

Design outcomes

Primary

Measure	Time frame
1.Congnitive function(12weeks, 24weeks) MMSE(Mini-mental State Examination) MENFIS(Mental Function Impairment Scale) 2.MRI(24weeks)	—

Secondary

Measure	Time frame
1.Effectiveness(12 weeks, 24 weeks) a:Caution function: Trail Making Test b:Daily living behavior (ADL): Barthel Index c:Measurable daily living activities (IADL) scale d:Behavioral disorders associated with dementia, Mental symptoms (BPSD): NPI-Q (Neuropsychiatric Inventory) e:Care burden: Zarit nursing care burden scale 2.Safety a:blood biochemical test(12 weeks, 24 weeks) b:Drink Record(everyday)	—

Measure

Time frame

1.Effectiveness(12 weeks, 24 weeks) a:Caution function: Trail Making Test b:Daily living behavior (ADL): Barthel Index c:Measurable daily living activities (IADL) scale d:Behavioral disorders associated with dementia, Mental symptoms (BPSD): NPI-Q (Neuropsychiatric Inventory) e:Care burden: Zarit nursing care burden scale 2.Safety a:blood biochemical test(12 weeks, 24 weeks) b:Drink Record(everyday)

—

Countries

Japan

Contacts

Public ContactJunko Yokota

Kochi Medical School Hospital Pharmacy

jm-yokotaj@kochi-u.ac.jp088-880-2549

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026