Psychophysical and neuroimaging study on therapeutic effects of Neurotropin on pain

Psychophysical and neuroimaging study on therapeutic effects of Neurotropin on pain - Neuroimaging of Neurotropin action

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000028993

Enrollment

Registered

2017-09-04

Start date

2020-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic pain

Interventions

To administer 1 ampoule of Neurotropin intravenously in an acute manner to healthy controls. To administer 1 ampoule of Neurotropin intravenously in an acute manner to patients with chronic pain. To a

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients with chronic pain with a numerical rating scale more than or equal to 3 for longer than 3 months. 2. Age- and gender-matched adults without any pain.

Exclusion criteria

Exclusion criteria: 1. A person with known history of allergic reaction to Neurotropin. 2. A person with contraindications against MRI such as claustrophobia, pregnancy, pacemakers or metals in the body.

Design outcomes

Primary

Measure	Time frame
1. Indices of offset analgesia 2. Cerebral activation associated with offset analgesia 3. Cerebral functional and anatomical connectivity 4. Cerebral blood flow 5. Voxel-based morphometry	—

Countries

Japan

Contacts

Public ContactJiro Kurata

The Jikei University School of Medicine Department of Anesthesiology

jkurata@plum.plala.or.jp03-3433-1111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026