Healthy adults
Conditions
Interventions
-Oral administration of an active drink every day for 4 weeks. -A 4-week washout period. -Oral administration of a placebo drink every day for 4 weeks.
-Oral administration of a placebo drink ever
Sponsors
Kao Corporation
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: Healthy male
Exclusion criteria
Exclusion criteria: -Subjects with photosensitive dermatitis. -Subjects with clinically-significant disorder at the test site -Subjects who go to hospital regularly or routinely taking oral medicine for disease: gastrointestinal system, liver, kidney, heart, and blood pressure. -Subjects who are routinely taking oral medicine for sunburn, chloasma, and freckles. -Subjects who are deemed inappropriate to participate in this study by the principle investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| -Evaluation of anti-inflammatory effect after 3 weeks of HB35FA administration. | — |
Secondary
| Measure | Time frame |
|---|---|
| -Change of inflammatory markers in the stratum corneum after 3 weeks of HB35FA administration. -Change of fecal microbiome and metabolome after 4 weeks of HB35FA administration. -Change of blood inflammatory markers after 4 weeks of HB35FA administration. | — |
Countries
Japan
Contacts
Public ContactTetsuya Kuwano
Kao Corporation R&D -Core Technology- Biological Science Research
Outcome results
None listed