Reflex esophagitis
Conditions
Interventions
Vonoprazan 20mg oral once a day, 4weeks
Esomeprazole 20mg oral once a day, 4weeks
Sponsors
Ikoma Gastorenteroproctorogy Clinic
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.The patients aged 20 years or older. 2.The patients who are diagnosed as having reflux esophagitis by physician. 3.The patients who have GERD symptom (heartburn or acid regurgitation) at least once a week.
Exclusion criteria
Exclusion criteria: 1.The patients with warning signs such as vomiting, gastrointestinal bleeding and sudden weight loss. 2.The patients with confirmed or suspected malignant diseases. 3.The patients with a history of gastrointestinal resection of vagotomy. 4.The patients with a history of irritable bowel syndrome. 5.The patients whose participation in this study would be contraindicated due to complications such as serious heaptic, renal or heart disease. 6.The Pregnant patients or possibly pregnant patients. 7.The patients prohibited the participant of this study by their attending physicians. 8.The patients who took esomeprazole or vonoprazan within 4 weeks.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The change of total score evaluated using FSSG | — |
Countries
Japan
Contacts
Public ContactTsutomu Masuda
Ikoma Gastorenteroproctorogy Clinic Gastroenterology
Outcome results
None listed