Suitability of propofol-remifentanil pharmacodynamic interaction model

Suitability of propofol-remifentanil pharmacodynamic interaction model - Suitability of propofol-remifentanil pharmacodynamic interaction model

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000028961

Enrollment

100

Registered

2017-10-01

Start date

2018-02-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gynecological disease

Interventions

epidural anesthesia transversus abdominis plane block

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: laparoscopic gynecorosical surgery under general aneathesia ASA1-2

Exclusion criteria

Exclusion criteria: height<150cm, weight<40kg, BMI>30, during pregnancy, during lactation, take antipsychotic drug, severe heart and/or renal failure, vasopressors in the operation, continuous unstable hemodynamic parameter (sBP>200mmHg, sBP<80mmHg, HR<40bpm)

Design outcomes

Primary

Measure	Time frame
The effect site concentrations of propofol and remifentanil(Loss of consiousness, insertion of a laryngoscopy, recovery of consiousness)	—

Secondary

Measure	Time frame
Blood pressure, Heart rate, The noxious stimulus response index (Loss of consiousness, insertion of a laryngoscopy, recovery of consiousness)	—

Countries

Japan

Contacts

Public ContactAmi Sugawara

Asahikawa Medical University Department of Anesthesiology and Critical care

asugawara@asahikawa-med.ac.jp0166-68-2583

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026