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A study to investigate the effects of Bifidobacteria on stress relief: a randomized, double-blind, placebo-controlled, parallel-group comparative study.

A study to investigate the effects of Bifidobacteria on stress relief: a randomized, double-blind, placebo-controlled, parallel-group comparative study. - Effects of Bifidobacteria on stress relief.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000028941
Enrollment
120
Registered
2018-04-01
Start date
2017-08-31
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

Ingestion of supplement containing Bifidobacteria for 8 weeks. Ingestion of placebo for 8 weeks.

Sponsors

Matsumoto Junior College
Lead Sponsor
Matsumoto Health Lab
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Healthy men and women aged more than 18 years, less than 65 years.

Exclusion criteria

Exclusion criteria: 1)Subject who is under medication for chronic disease. 2)Subject with hepatic disease, renal dysfunction, cardiovascular disorder, gastrointestinal disorder, respiratory dysfunction, blood disease, autoimmune disease, endocrine disease, metabolic disease and these severe medical history. 3)Subject with serious allergy to specific medicine or food. 4)Subject who is pregnant or under lactation, or who is expected to be pregnant during the study. 5)Subject who constantly take medicines and/or supplements affecting gut microbiota. 6)Heavy drinker. 7)Subject who is ineligible due to physician's judgment.

Design outcomes

Primary

MeasureTime frame
Visual analog scale questionnaire

Secondary

MeasureTime frame
Saliva stress marker, POMS, Autonomic nervous activity.

Countries

Japan

Contacts

Public ContactTerumi Yamashita

Matsumoto Junior College Department of Nursing

mjc-t.yamasita@matsutan.ac.jp0263-58-4417

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026