Research on the effects of hyperthermia on physiological responses to hypoxia

Research on the effects of hyperthermia on physiological responses to hypoxia - Research on the effects of hyperthermia on physiological responses to hypoxia

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000028932

Enrollment

Registered

2018-01-01

Start date

2017-08-29

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adult males

Interventions

3000m simulated altitude (14.4% oxygen) exposure for 3 hours + Hyperthermia (~1.2 C increase in esophageal temperature) for 2 hours 3000m simulated altitude (14.4% oxygen) exposure for 3 hours + Normo

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: 1) age <= 20 years old to > 40 years old at the time of informed consent 2) volunteers who are fully informed of and understand the objectives, procedures, and possible risks of the study and provide the written voluntary consent to participate in the study.

Exclusion criteria

Exclusion criteria: 1) Diseases which need physical work restriction 2) Cardiovascular diseases, arrhythmia 3) Metabolic and endocrine disease 4) Hypertension (resting blood pressure, SBP > or = 160 mmHg, DBP > or = 100) 5) Smokers 6) Obesity (BIM <= 30 kg/m2) 7) Ineligible by a medical interview

Design outcomes

Primary

Measure	Time frame
heart rate, blood pressure, arterial oxygen saturation, carotid artery blood flow, plasma erythropoietin concentration	—

Countries

Japan

Contacts

Public ContactKazunobu Okazaki

Osaka City University Graduate School of Medicine Environmental Physiology for Exercise

okazaki@sports.osaka-cu.ac.jp06-6605-2950

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026