Study on Single Nucleotide Polymorphisms of Functional Proteins determining Absorption, Metabolism, and Excretion of Edoxaban.

Study on Single Nucleotide Polymorphisms of Functional Proteins determining Absorption, Metabolism, and Excretion of Edoxaban. - Single Nucleotide Polymorphisms and Edoxaban.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000028886

Enrollment

100

Registered

2017-10-01

Start date

2017-12-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-valvular atrial fibrillation

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with non-valvular atrial fibrillation receiving oral edoxaban therapy

Exclusion criteria

Exclusion criteria: Those who cannot give informed consent Patients younger than 20 years

Design outcomes

Primary

Measure	Time frame
Examine the relationship between functional SNP in CYP3A5, ABCB1 and ABCG2 and blood levels of oral edoxaban and determine their influence.	—

Countries

Japan

Contacts

Public ContactTakashi Ashihara

Shiga University of Medical Sciences Department of Cardiovascular Medicine

tashihar@gmail.com81-77-548-2213

Outcome results