cancer (cancer-related fatigue)
Conditions
Interventions
1. Dexamethasone 8mg by mouth once a day day 1-7, 4mg for day 8-14 2. Dexamethasone 6.6mg by venous injection once a day day 1-7, 3.3mg for day 8-14
Sponsors
National Cancer Center Hospital East
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: A diagnosis of advanced cancer (defined as metastatic or recurrent) with fatigue score 4 and more using NRS(0-10) 20 years and older Prognosis over 30 days No anti-cancer treatment plan Inpatient receiving palliative care Performance status 0-3 Conprehension of Japanese Provided written informed consent
Exclusion criteria
Exclusion criteria: Patients received corticosteroid therapies within 1 week Patients received surgery within 4 week Patients received radiation therapy within 2 week Patients received anti-tumor treatment within 2 week Patients had diabetes mellitus, active infection and cognitive disorder
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The change of FACIT-Fatigue subscale score at day 8 | — |
Secondary
| Measure | Time frame |
|---|---|
| The change of fatigue score The proportion of achievement of individual therapeutic goal The change of symptom scores the change of performance status Patients satisfaction Adverse events | — |
Countries
Japan
Contacts
Public ContactTomofumi Miura
National Cancer Center Hospital East Department of Palliative Medicine
Outcome results
None listed