Healthy people
Conditions
Interventions
Ingestion of the lactic acid bacteria stored in Nissin Foods A food 2 capsules per day for 9 weeks.
Ingestion of the lactic acid bacteria stored in Nissin Foods B food 2 capsules per day for 9 weeks.
Sponsors
Iwase Cosfa Co., Ltd.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Japanese adults aged from 30 to 49 years old at the time of informed consent was provided 2) Male and female 3) Type II or III of Fitzpatric Skin Type 4) Voluntary test participants who provided written informed consent
Exclusion criteria
Exclusion criteria: 1)Persons who are photosensitivity 2)Persons who take medications for light sensitivity of the skin 3)Persons who are prone to allergies for foods or have lactose intolerance 4)Persons who are a regular patient at the hospital for treatment in dermatological issues 5)Persons who have factors and symptoms of skin diseases on the skin of the evaluation site (diseases such as atopic dermatitis and urticaria, inflammation, eczema, etc., extreme sunburn history on the back), which may affect the test results 6)Persons who have subjective symptoms of severe anemia 7)Persons who are receiving treatment at a medical institution or those who judged to be in the relevant condition requires treatment 8)Persons who have the following medical history : severe diseases (such as sugar metabolism, lipid metabolism, liver function, renal function, heart, circulatory organs, respiratory organs, endocrine system, the nervous system), psychiatric diseases, or alcohol and drug dependence 9)Persons who have received skincare and spa treatment to the evaluation site within the past 4 weeks 10)Persons who have been exposed to ultraviolet rays beyond their daily life within the past 2 months 11)Persons who have irregular or disturbed life style such as night shifts 12)Persons who have participated in other clinical studies within the past 4 weeks 13)Persons who are pregnant or lactating, or who hope to become pregnant during the test 14)Persons who have difficulties with filling the subject diary 15)Persons who are identified inappropriate for the test by the investigator 16)Persons who smoke 17)Persons who continuously ingested health foods, supplements, nutrition-enhanced foods (especially, yoghurt, lactic acid bacteria preparations, vitamins, polyphenols, etc) within the past 4 weeks 18)Persons whose menstrual cycle is disturbed within the past 2 months 19)Persons who consume 40 g or more per day for males and 20 g or more per day for females by pure alcohol conversion
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1) MED (minimal erythemal dose) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Erythemal and pigmentation in the MED site and nearby areas of the MED site 2) Erythemal and pigmentation in the 1.5 MED site and nearby areas of the MED site 3) Antioxidant effect: Catalase activity in the stratum corneum of the exposed area 4) Questionnaire for use feedbacks 5) Adverse events | — |
Countries
Japan
Contacts
Public ContactMasafumi Takano
DRC Co., Ltd. Product Testing Department
Outcome results
None listed