An exploratory study analyzing the effect of abatacept therapy on serostatus in Japanese real world as well as the relationship between efficacy evaluation with clinical parameters and changes in serostatus

An exploratory study analyzing the effect of abatacept therapy on serostatus in Japanese real world as well as the relationship between efficacy evaluation with clinical parameters and changes in serostatus - An exploratory study analyzing the effect of abatacept therapy on serostatus

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000028804

Enrollment

100

Registered

2017-09-01

Start date

2017-08-31

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

rheumatoid arthritis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: RA patients who meet 2010 ACR/EULAR Classification Criteria for RA Patients who consulted at Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences and research cooperation institutions between June 2013 and June 2017 >Abatacept arm Patients who meet Japan College of Rheumatology guidelines for the use of abatacept against RA and started abatacept treatment Patients who were able to be follow-upped for 12 months after introduction of the therapy Patients who had no history of biological agents >MTX arm (Control arm) Patients who were able to be follow-upped for 12 months after introduction of the therapy Patients who were matched with age and disease duration with abatacept arm

Exclusion criteria

Exclusion criteria: Patients who are judges as inappropriate for enrollment to the study by the investigator

Design outcomes

Primary

Measure	Time frame
The seroconversion rate of IgM-ACPA at 12 months after treatment	—

Countries

Japan

Contacts

Public ContactShin-ya Kawashiri

Nagasaki University Graduate School of Biomedical Sciences Department of Community Medicine

shin-ya@nagasaki-u.ac.jp095-819-7189

Outcome results