The influence of herbs on pain threshold

The influence of herbs on pain threshold - The influence of herbs on pain threshold

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000028798

Enrollment

100

Registered

2017-08-23

Start date

2016-11-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adult

Interventions

Menthol is applied to the inside of the forearm, and pain equivalent current value is measured with PainVision 3 and 10 minutes later (Menthol group) Mentholatum group Ethanol group Menthol + Menthola

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Healthy adult 2.Subjects whose The American Society of Anesthesiologists physical status (ASA-PS) is 1 and 2. 3.Subjects who agree to participate in this study with a written informed consent.

Exclusion criteria

Exclusion criteria: 1.Subjects who disagree to participate in this study. 2.Subjects who are allergic to menthol, mentholatum, ethanol. 3.Subjects with skin disorders such as atopic dermatitis 4.Subjects with complications of neurological disorders such as neurological diseases and severe diabetes 5.Subjects taking analgesics 6.Subjects conducting topical therapy to the forearm

Design outcomes

Primary

Measure	Time frame
Three minutes after application of topical medicine, pain equivalent current value is measured by PainVision	—

Countries

Japan

Contacts

Public ContactYamauchi Masanori

Tohoku University Department of Anesthesiology

yamauchi@med.tohoku.ac.jp022-717-7321

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026