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Silent cerebral microvascular disease and longitudinal risK of cognitive decline in Atrial Fibrillation study

Silent cerebral microvascular disease and longitudinal risK of cognitive decline in Atrial Fibrillation study - SKAF Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000028754
Enrollment
200
Registered
2017-10-01
Start date
2017-11-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-valvular atrial fibrillation

Interventions

The patient who takes Edoxaban The patient who does not take the anticoagulant

Sponsors

DAIICHI SANKYO COMPANY
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) The patient who was given a definitive diagnosis of Non-valvular atrial fibrillation (NVAF) 60 years or older (2) The patient who hasn't had a Cerebral infarction or a dementia in the past (3) The patient that a written agreement was provided

Exclusion criteria

Exclusion criteria: (1) The patient who participates in an intervention examination now or plans it (2) The patient who is given a definitive diagnosis of mitral stenosis (3) he patient who has an Artificial valve (aMachine valve or a Bioprosthetic valv) (4) The patient who received art of heart intervention 1 month before enrolled (5) The patient who contraindications of MRI inspection (6) The patient who has a depression (7) The patient who is remaining 2 years because of some diseases (8) The patient who is inappropriateness of this study judged by the doctor

Design outcomes

Primary

MeasureTime frame
The onset of asymptomatic cerebrovascular disorder situation during the observation period

Countries

Japan

Contacts

Public ContactYusuke Kondo

Chiba University Graduate School of Medicines Department of Advanced Cardiovascular Therapeutics

shimokita9933@msn.com0432262847

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026