Efficacy of polyglycolic acid sheet and steroid injection for preventing stricture in sub-circumference ESD.

Efficacy of polyglycolic acid sheet and steroid injection for preventing stricture in sub-circumference ESD. - PGA steroid study

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000028747

Enrollment

Registered

2017-08-21

Start date

2017-08-21

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal cancer including intraepithelial neoplasia

Interventions

PGA sheet and steroid injection

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1 The patients predicted to resect with a mucosal defect greater than or equal to 5/6 of the esophageal circumference 2 Over 20 years old 3 obtain informed consent

Exclusion criteria

Exclusion criteria: 1 Mucosal defect < 5/6 circumference 2 Entire circumferential lesion 3 Patients who resected entire curcumference 4 take oral steroid therapy 5 Mental disease 6 Pregnancy 7 Allergy for PGA or fibrin glue 8 other reasons which made the subject ineligible to participate in this study, at the discretion of the chief investigator.

Design outcomes

Primary

Measure	Time frame
Stricture rate on 8 weeks after ESD	—

Secondary

Measure	Time frame
1 Numbar of balloon dilatation 2 adverse events 3 Stricture rate when ulceration healed to scar formation 4 Stricture rate on 6 months after ESD	—

Countries

Japan

Contacts

Public ContactYasuaki Nagami

Osaka City University Graduate school of Medicine Gastroenterology

yasuaki-75@med.osaka-cu.ac.jp06-6645-3811

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026