Analysis an association between host immune response to rotavirus vaccine and intestinal flora

Analysis an association between host immune response to rotavirus vaccine and intestinal flora - Analysis an association between host immune response to rotavirus vaccine and intestinal flora

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000028742

Enrollment

Registered

2017-08-21

Start date

2017-09-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infants in NICU/GCU that meet to the requirements for rotavirus vaccine.

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Infants in NICU/GCU that meet to the requirements for rotavirus vaccine. 2. Parental written informed consent to participate in the study is required.

Exclusion criteria

Exclusion criteria: 1. Subjects with contraindications or adverse effects. 2. Subjects who have a serious gastrointestinal surgical history or congenital gastrointestinal malformation. 3. Any other medical reasons judged by the principal investigator.

Design outcomes

Primary

Measure	Time frame
Correlation between intestinal flora and fecal shedding of rotavirus and host immune response after vaccination.	—

Secondary

Measure	Time frame
A level of various cytokines/ chemokines, immunity factors contained in breast milk and blood.	—

Countries

Japan

Contacts

Public ContactTetsushi Yoshikawa

Fujita Health University School of Medicine Dept. of Pediatrics

tetsushi@fujita-hu.ac.jp+81-562-93-9251

Outcome results