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A multicenter retrospective study on efficacy and safety of salvage surgery for primary lung cancer

A multicenter retrospective study on efficacy and safety of salvage surgery for primary lung cancer - A multicenter retrospective study on efficacy and safety of salvage surgery for primary lung cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000028741
Enrollment
400
Registered
2017-08-21
Start date
2016-10-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

primary lung cancer

Interventions

None listed

Sponsors

Division of General Thoracic Surgery, Integrative Center of General Surgery, Gunma University Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: A) Patient who underwent salvage surgery after definitive CRT/RT, stereotactic radiation, ion beam therapy. 1) Patient who underwent salvage surgery between 1/1/2010 and 12/31/2015. 2) Primary lung cancer was proven pathologically at any point in time. 3) Patient who could not complete the initial therapy because of adverse event or complication is also eligible, if the initial therapy was intended radical treatment. 4) Three years passed after salvage surgery. B) Patient who underwent salvage surgery after molecular targeted therapy(EGFR-TKI or ALK inhibitor). 1) Patient who underwent salvage surgery between 1/1/2010 and 12/31/2015. 2) Primary lung cancer was proven pathologically at any point in time. 3) EGFR-TKI or ALK inhibitor was administrated. 4) Three years passed after salvage surgery. 5) EGFR mutation status and ALK rearrangement status do not matter.

Exclusion criteria

Exclusion criteria: 1) Patient treated as induction therapy intentionally. 2) Patient who underwent resection not for local lesion (other than lung or regional lymph node). 3) Patient who was treated with molecular targeted therapy other than EGFR-TKI or ALK inhibitor as molecular targeted therapy. 4) Patient who withdrew the consent of this study. 5) Patient who was considered inappropriate to this study by attending doctor.

Design outcomes

Primary

MeasureTime frame
3-year overall survival rate

Secondary

MeasureTime frame
Adverse event, Incidence of complications, Perioperative mortality, 3-year recurrence free survival rate, Median survival time

Countries

Japan

Contacts

Public ContactYoichi Ohtaki, Kimihiro Shimizu

Gunma University Hospital Division of General Thoracic Surgery, Integrative Center of General Surgery

yohtakiadvanced@gmail.com027-220-8245

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026