Clinical trial of prevention for PCI-related myocardial infarction evaluating index of microvascular resistance in stable coronary artery disease. -Effect of Fasudil, a selective Rho-kinase inhibitor-

Clinical trial of prevention for PCI-related myocardial infarction evaluating index of microvascular resistance in stable coronary artery disease. -Effect of Fasudil, a selective Rho-kinase inhibitor- - Clinical trial of prevention for PCI-related myocardial infarction evaluating index of microvascular resistance in stable coronary artery disease. -Effect of Fasudil, a selective Rho-kinase inhibitor-

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000028739

Enrollment

Registered

2017-10-01

Start date

2017-10-04

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stable coronary artery disease

Interventions

intracoronary single administration of 30mg of Fasudil intracoronary single administration of normal saline

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1)stable coronary artery disease (2)stenosis in left coronary artery (3)pressure wire enable to pass the lesion (4)20 years old and older (5)male or female

Exclusion criteria

Exclusion criteria: (1) severe anemia or infection, malignancy, decompensated congestive heart failure (2) previous myocardial infarction in the target vessel (3) target vessel is a donar or recipient of collateral artery (4)systolic blood pressure under 80mmHg (5)bronchial asthma or allergy for adenosin triphosphate (6) left main coronary trunk lesion or severe stenosis with contrast delay (7) severe renal or liver dysfunction (8) allergy for Fasudil

Design outcomes

Primary

Measure	Time frame
index of microvascular resistance	—

Secondary

Measure	Time frame
high sensitive troponin T	—

Countries

Japan

Contacts

Public ContactYoku Kikuchi

Tohoku University Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan

ykikuchi911@cardio.med.tohoku.ac.jp022-717-7153

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026