Confirmation of the unpleasant feeling reduction effect of the nose by study food intake:A randomized, double blinded, placebo controlled, and parallel group comparison study

Confirmation of the unpleasant feeling reduction effect of the nose by study food intake:A randomized, double blinded, placebo controlled, and parallel group comparison study - Confirmation of the unpleasant feeling reduction effect of the nose by study food intake

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000028724

Enrollment

Registered

2017-08-19

Start date

2017-08-20

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adults

Interventions

Ingestion of food including beta-glucan (low dose) for 12 consecutive weeks Ingestion of food including beta-glucan (high dose) for 12 consecutive weeks Ingestion of food including uncrystallized beta

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1)Adult men and women from 20 to 64 years of age (2)Subjects with discomfort of nose (sneeze,runny nose,nasal) (3)Subjects positive for specific IgE (RAST) against house dust or mite. (4)Subjects who the discomfort of the nose is "light" and "slightly heavy" in JRQLQ

Exclusion criteria

Exclusion criteria: (1)Subjects who routinely use health food including functional substance richly (2)Subjects who routinely take foods or medicines affecting the test result (3)Subjects judged as unsuitable for the study who cannot stop an intake of the food which may have an influence on the discomfort of the nose (4)Subjects who are under treatment or have a history of serious disease(e.g., diabetes, liver disease, kidney disease, or heart disease) (5)Subjects having a disease under treatment or a history of serious diseases for which medication was required (6)Subjects having possibilities for emerging allergy related to the study (7)Subjects judged as unsuitable for this study based on the results of clinical examination or cardiopulmonary abnormality (8)Subjects who are judged as unsuitable for the study based on the results of clinical and physical examination on preliminary examination (9)Subjects who have participated in other clinical study within the last one month prior to the current study or are planned to participate in other clinical study after informed consent for the current study (10)Subjects who intend to become pregnant or lactating (11)Subjects who are judged as unsuitable for the study based on the results of lifestyle questionnaire (12)Subjects judged as unsuitable for the study by the investigator for other reasons

Design outcomes

Primary

Measure	Time frame
JRQLQ	—

Secondary

Measure	Time frame
Doctor views of the nose Examination for nasal mucus Discomfort diary of the nose	—

Countries

Japan

Contacts

Public ContactChiharu Goto

TTC Co.,Ltd. Clinical Research Planning Department

c.goto@ttc-tokyo.co.jp03-5459-5329

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026