A pilot study of prognostic significance of arterial 18F-NaF and 18F-FDG uptake in patients with aortic aneurysm

A pilot study of prognostic significance of arterial 18F-NaF and 18F-FDG uptake in patients with aortic aneurysm - prognostic significance of 18F-NaF and 18F-FDG uptake in aortic aneurysm

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000028647

Enrollment

150

Registered

2017-08-12

Start date

2018-09-05

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

aortic aneurysm

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. over 20 years old 2. Patients with aortic aneurysm in which diameter is over 45 mm for thoracic aortic aneurysm or 40 mm for abdominal aortic aneurysm 3. Patients with aortic aneurysm which is judeged by ardiovascular surgens not to be necessary for surgery for at least 1 year at the time of informed consent. 4. Patient who agree to participate in this study.

Exclusion criteria

Exclusion criteria: 1. Allergic to FDG and NaF solution 2. History of vasculitis, autoimmune disease, and collagen disease 3. History of Marfan syndrome 4. Hisotyr of chemotherapy and radiation therapy within 8 weeks 5. Definitly or potentially pregnant woman or lactating woman 6. Uncontrolable diabetes mellitus 7. Poor performance status 8. Difficulty in coming to hospital because of poor physical activity 9. History of pshychiatric disorders

Design outcomes

Primary

Measure	Time frame
Relationship between the uptake of 18F-NaF and 18F-FDG and the enlargement rate of aortic diameter 24 months after PET examinations in the patients with aortic aneurysm.	—

Countries

Japan

Contacts

Public ContactTakehiro Nakahara

Keio University School of Medicine Department of Diagnostic Radiology

takehiro.nakahara@keio.jp03-5363-3837

Outcome results