The investigation of reliability and validity in the N-terminal fragment of titin in urine as muscle damage markers for eccentric exercise-induced muscle damage

The investigation of reliability and validity in the N-terminal fragment of titin in urine as muscle damage markers for eccentric exercise-induced muscle damage - The investigation of reliability and validity in the N-terminal fragment of titin in urine

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000028633

Enrollment

Registered

2017-08-12

Start date

2017-08-30

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Eccentric exercise-induced muscle damage

Interventions

The intervention period will be 1 day, and until the 2 to 7 day will be the observation duration. Contents of the intervention will work out 3 sets of eccentric contraction exercise 10 times.

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: 1.Those who obtain written consent from the subject concerning research participation. 2.The 20 to 30 years old healthy male.

Exclusion criteria

Exclusion criteria: 1.Those who regularly conduct training during the past half year. 2.Those who has injury sickness which impedes the performance of this research. 3.Persons who are taking supplements, medicines, etc. on a daily basis. 4.Those who experienced blood collection of 200 ml or more within 12 weeks of the start of the study.

Design outcomes

Primary

Measure	Time frame
Titin fragment concentration in urine during 24 to 48 hours after eccentric exercise	—

Secondary

Measure	Time frame
muscle soreness Range of motion upper arm circumference Creatine kinase activity Aldolase activity Myoglobin concentration Aspartate aminotransferase activity Alanine transferase activity Lactate dehydrogenase activity	—

Countries

Japan

Contacts

Public ContactShota kato

Waseda University Sport science graduate course

kato@yahoo.co.jp08030438030

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026