Prostate cancer
Conditions
Interventions
Carbon-ion radiotherapy of 40Gy(RBE)in 4 fraction within 1 week.
Sponsors
QST Hospital, National Institutes for Quantum Science and Technology Treatment division
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1) Local recurrence biopsy proven prostate cancer after radical radiotherapy. 2) rT2a-T2bN0M0 according to MRI, CT and bone scintigram (visible lesion in MRI). 3) PSA < 8.0 ng/ml before biopsy proven local recurrence after biochemical relapse. 4) PSA doubling time > 6 months. 5) Teststeron value within 30 days before starting this treatment > within normal lower limit. 6) Performance Status (ECOG) of 0-1. 7) Approved by document.
Exclusion criteria
Exclusion criteria: 1) Other salvage therapy has been performed except for the case with positive local recurrence by biopsy after discontinuance of hormonal therapy 2) Presence of biopsy proven separate lesions except for visible lesion in MRI. 3) Having at least one factor of GS>9, T3b and PSA > 40 ng/ml before initial radical radiotherapy. 4) occuring Grade 3 or more severe adverse effect after initial radical radiotherapy. 5) Ineligible dose constraint of risk organs 6) Considered to be castration resistant prostate cancer 7) Presence of active double cancer
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Acute and late adverse effect | — |
Secondary
| Measure | Time frame |
|---|---|
| Biochemical relapse free survival, overall survival, Clinical relapse free survival, cancer specific survival, dose-volume evaluation, QOL evaluation | — |
Countries
Japan
Contacts
Public ContactGoro Kasuya
QST Hospital, National Institutes for Quantum Science and Technology Treatment division
Outcome results
None listed