The effect of protein supplementation at breakfast or supper for 12 weeks beyond habitual intakes on lean body mass and bone mineral density.

The effect of protein supplementation at breakfast or supper for 12 weeks beyond habitual intakes on lean body mass and bone mineral density. - The effect of protein supplementation at breakfast or supper for 12 weeks beyond habitual intakes on lean body mass and bone mineral density.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000028612

Enrollment

100

Registered

2017-08-10

Start date

2017-09-10

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sarcopenia, osteoporosis

Interventions

Breakfast (0600 - 1000): intake of milk protein 10 g/day for 12 weeks Supper (1800 - 2200): intake of milk protein 10 g/day for 12 weeks Breakfast placebo (0600 - 1000) Supper placebo (1800 - 2200)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Above 65 years older adults 2) Gives informed consent, agrees to be randomly assigned

Exclusion criteria

Exclusion criteria: 1) Impaired cardiac (e.g., with cardiac pacemaker implants), kidney functions. 2) Physically active lifestyle 3) Intake of lipid and/or glucose lowering medication 4) Intake of Antipsychotics, Hypnotic, Steroids 5) Smoking habit 6) milk allergy 7) Phenylketonuria 8) Xylocaine allergy 9) Judged ineligible by a medical doctor. 10) History or presence of osteoporosis and compression fracture 11) Individuals with acute orthopedic pain and neurological symptom 12) Obesity (BMI>35kg/m2) and sleep apnea syndrome 13) High blood pressure (SBP:above140mmHg, and DBP:above 90mmHg)

Design outcomes

Primary

Measure	Time frame
The following measures would be conducted before and after 12 weeks of intervention. 1) Lean body mass and bone mineral density	—

Secondary

Measure	Time frame
1) bone metabolism markers 2) myokine 3) clock-gene 4) Physical functional parameter 5) physical activity(accelerometer) 6) morningness-eveningness type, the center for epidemiologic studies depression scale, pittsburgh sleep quality index (questionaire)	—

Countries

Japan

Contacts

Public ContactHyeon-Ki Kim

Waseda University Organization for University Research Initiatives

hk.kim@aoni.waseda.jp03-5369-7318

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026