Effects of insulin on thermoregulation after sugar intake

Effects of insulin on thermoregulation after sugar intake - Effects of insulin on thermoregulation after sugar intake

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000028611

Enrollment

Registered

2017-08-31

Start date

2015-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Target population: Persons with an attenuated thermoregulation under the heat

Interventions

Intranasal insulin administration Regular Insulin (Novolin R, 100 IU/mL) is administrated to nares side-to-side by a nasal spray every minute (total 16 times, 160 IU) Placebo control Normal saline i

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Healthy adults

Exclusion criteria

Exclusion criteria: Diabetes Metabolic and endocrine disease Hypertension (SBP > or = 140 mmHg, DBP > or = 90) Cardiovascular diseases Obesity (BMI, males > or = 25 kg/m2, females > or = 30 kg/m2) Smoking Conditions difficult to perform measurements Ineligible by a medical interview

Design outcomes

Primary

Measure	Time frame
Primary outcome is thermoregulatory response during 60 minutes of passive heating after sugar ingestion.	—

Secondary

Measure	Time frame
Key secondary outcomes are heart rate, blood pressure, oxygen consumption, and blood constituents.	—

Countries

Japan

Contacts

Public ContactKazunobu Okazaki

Osaka city university graduate school of medicine Environmental physiology for exercise

okazaki@sports.osaka-cu.ac.jp06-6605-2950

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026