Evaluation of the effect of lactic acid bacteria on glucose metabolism in subjects with borderline diabetes

Evaluation of the effect of lactic acid bacteria on glucose metabolism in subjects with borderline diabetes - Evaluation of the effect of lactic acid bacteria on glucose metabolism in subjects with borderline diabetes

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000028600

Enrollment

Registered

2017-08-10

Start date

2017-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy volunteers

Interventions

Intake of granulated powder containing Pediococcus pentosaceus LP28 and dextrin (2 g/day) for 12 weeks. Intake of granulated powder of dextrin (2 g/day) for 12 weeks.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 140<= OGTT-2h <200 mg/dL

Exclusion criteria

Exclusion criteria: 1) HbA1c>=6.5% 2) Taking medicines or receiving health guidance for hypertension, diabetes, and/or hyperlipidemia 3) Taking drugs or functional food that may affect the trial 4) Participation in any clinical trial within 90 days of the commencement of the trial 5) In pregnancy or nursing a child 6) Judged as ineligible by clinical investigators

Design outcomes

Primary

Measure	Time frame
12-week change in OGTT-2h	—

Secondary

Measure	Time frame
12-week changes in AUC, Cmax and Tmax of blood glucose and insulin in OGTT, insulinogenic index, FBS, HOMA-R, HbA1c, glycoalbumin, visceral fat area, body fat percentage, abdominal circumference	—

Countries

Japan

Contacts

Public ContactFumiko Higashikawa

Hiroshima University, Institute of Biomedical & Health Sciences Project Research Center for Clinical Trial and Preventive Medicine

fumiko@hiroshima-u.ac.jp082-257-1533

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026