Prospective study to evaluate the clinical outcome of POEM combined with endoscopic anti-reflux surgery.

Prospective study to evaluate the clinical outcome of POEM combined with endoscopic anti-reflux surgery. - Endoscopic anti-reflux surgery and POEM

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000028567

Enrollment

100

Registered

2017-08-08

Start date

2017-08-10

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

esophageal achalasia

Interventions

conventional POEM adding endoscopic anti-reflux surgery

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who are planning to undergo POEM surgery, and who can recieve informed consent document.

Exclusion criteria

Exclusion criteria: 1: severe achalasia (ex. sigmoid type) 2: non-achalasia 3: taking anti-thrombotic agents 4: who has severe complications(Diabetes, Heart disease, Strokes, Neurological disorder, Psychosis, etc.) 5: a history of complications with anesthesia 6: pregnant and breast-feeding 7: who cannot withdraw PPI 8: consent can not be obtained 9: other inappropriate cases

Design outcomes

Primary

Measure	Time frame
1: The reslut of multichannel intraluminal impedance pH monitoring(MII-pH) 2: endoscopic findings 3: symptoms 4: whether the patients needs PPI or not in 2 months later and 1 year later from the surgery. 5: QERD-Q score and F-scale	—

Secondary

Measure	Time frame
1: The clinical outcome of POEM(Eckardt score, esophageal manometry, esophagography) 2: Adverse event due to surgery	—

Countries

Japan

Contacts

Public ContactAkiko Toshimori

Showa University Koto Toyosu Hospital Digestive disease center

akikoueno@med.showa-u.ac.jp03-6204-6000

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026