Association of serum protein-bound uremic toxin levels with uremic pruritus and quality of life in hemodialysis patients

Association of serum protein-bound uremic toxin levels with uremic pruritus and quality of life in hemodialysis patients - PBUTs and pruritus/QOL in HD patients

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000028464

Enrollment

133

Registered

2017-07-31

Start date

2017-07-31

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic kidney disease undergoing hemodialysis treatment

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Chronic kidney disease patients undergoing hemodilysis treatment 2. Participants provided written informed consent

Exclusion criteria

Exclusion criteria: 1. Participants who do not recieve hemodialysis treatment.

Design outcomes

Primary

Measure	Time frame
Association of protein-bound uremic toxins, such as indoxyl sulfate, p-cresyl sulfate and phenyl sulfate, with degree of pruritus from visual analog scale and 5D itch scale.	—

Secondary

Measure	Time frame
Association of protein-bound uremic toxins, such as indoxyl sulfate, p-cresyl sulfate and phenyl sulfate, with quality of life score using KDQOL. All cause mortality, hospitalization owing to cardiovascular event and infection during two year observation.	—

Countries

Japan

Contacts

Public ContactSuguru Yamamoto

Niigata University Medical and Dental Hospital Division of Blood Purification Therapy

yamamots@med.niigata-u.ac.jp025-227-2200

Outcome results