Hangover
Conditions
Interventions
Loxoprofen 60mg once orally
Placebo
Sponsors
Japan Society of Clinical Research
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Meet all of the following 1. Medical doctor in Japan 2. Participants who can drink alcohol and may experience hangovers with the symptom of general fatigue during the study period 3. Participants who are able to understand the study and gave informed consent on their own
Exclusion criteria
Exclusion criteria: Current or history of 1. Peptic ulcer 2. Haematological disorder 3. Abnormal liver function 4. Abnormal kidney function 5. Abnormal heart function 6. Malignancy 7. Hypersensitivity to loxoprofen sodium 8. Aspirin-induced asthma 9. Psychiatric disorder 10. Steroid usage 11. Routine usage of NSAIDs 12. Routine usage of other pain killer, including aspirin 13. Routine usage of antiemetic 14. Possibility of pregnancy 15. Participant in a clinical study within 3 months 16. Other inappropriate candidates judged by investigators
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The difference in severity of general fatigue before and 3 hours after taking the test drugs using VAS | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. The difference in the severity of headache before and 3 hours after taking the test drugs using VAS 2. The difference in the severity of nausea before and 3 hours after taking the test drugs using VAS 3. The incidence of an adverse event 4. The changes in the impression of performing a clinical study before and after participating in this randomised controlled trialusing VAS | — |
Countries
Japan
Contacts
Public ContactMasahiko Hara
Japan Society of Clinical Research Secretariat
Outcome results
None listed