Hypertension
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Twenty apparently healthy men and women aged 40-65 years with a high normal BP or mild hypertension ) who were not receiving antihypertensive treatment were enrolled in this study
Exclusion criteria
Exclusion criteria: History of CVD, malignant disease, or other chronic disease including CVD risk factors other than mild hypertension (i.e., dyslipidemia, diabetes mellitus, and chronic kidney disease), BMI mor than 30 kg/m2, current smoker, habitual use of antioxidant supplements, milk or chocolate or cacao allergy, and premenopausal
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| home blood pressure(HBP), HBP variability, vasculare function, insulin sensitivity (IS) | — |
Secondary
| Measure | Time frame |
|---|---|
| interaction between DC and IS | — |
Countries
Japan
Contacts
Tokyo Medical University Department of Cardiology