A prospective study of evaluation of radiation induced myocardial injury after chemoradiotherapy for esophageal cancer using dual-radioisotope SPECT

A prospective study of evaluation of radiation induced myocardial injury after chemoradiotherapy for esophageal cancer using dual-radioisotope SPECT - A prospective study of evaluation of radiation induced myocardial injury after chemoradiotherapy for esophageal cancer using dual-radioisotope SPECT

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000028331

Enrollment

Registered

2017-07-24

Start date

2016-08-19

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal cancer

Interventions

To perform 99mTc-tetrofosmine and 123I-BMIPP SPECT/CT before and 1 year after the radiotherapy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)Histologically-proven esophageal cancer. 2)Adaptation of Definitive or pre-operative chemoradiotherapy with equal or more than 50 Gy 3)Thoracic esophageal cancer 4)Enable to perform myocardial SPECT/CT 5)ECOG Performance status 0 to 2 6)Aged 20 to 75 7)Written informed consent

Exclusion criteria

Exclusion criteria: 1)History of heart disease 2)History of radiation to the mediastinum 3)Lactating or pregnant women 4)Psychiatric medication 5)Severe complications 6)Inadequate to adapt this trial

Design outcomes

Primary

Measure	Time frame
To evaluate the change of SPECT between before and after radiotherapy	—

Countries

Japan

Contacts

Public ContactMasahiro Inada

Kindai University Faculty of Medicine Department of Radiation Oncology,

im022012@med.kindai.ac.jp072-366-0221

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026