Evaluation of reaction and adverse events in Trichuris suis ova therapy

Evaluation of reaction and adverse events in Trichuris suis ova therapy - A Randomised double-blind placebo-controlled trial of Trichuris suis ova therapy in Japanese healthy adults

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000028248

Enrollment

Registered

2017-09-01

Start date

2017-09-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adult

Interventions

TSO administration TSO placebo administration

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: Healthy adult male(A person with no current and ongoing medication, without history of disease with recurrence or relapse.)

Exclusion criteria

Exclusion criteria: A person who previously administered TSO and had severe adverse events. One who was judged inappropriate by the attending physician.

Design outcomes

Primary

Measure	Time frame
Frequency of adverse events during 56 days after administration of single dose of Trichuris suis ova.	—

Secondary

Measure	Time frame
Frequency of infection by T. suis on day 56 after administration of single dose of T. suis ova.	—

Countries

Japan

Contacts

Public ContactTokio Hoshina

The Jikei University School of Medicine Department of Infectious Disease and Control

tohoshina@jikei.ac.jp03-3433-1111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026