Involvement of brain volume and stress-related hormone in cognitive impairment with age-related hearing loss

Involvement of brain volume and stress-related hormone in cognitive impairment with age-related hearing loss - Association between stress-related hormone and cognitive impairment with age-related hearing loss

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000028241

Enrollment

100

Registered

2017-08-01

Start date

2017-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

age-related hearing loss

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1 patients visiting in Gifu University Hospital, Department of Otolaryngology 2 patients aged more than 60 years olds 3 patients with mild hearingl loss of more than 25dB

Exclusion criteria

Exclusion criteria: 1) patients with ear drum perforation, secretion in middle ear 2) patients with congenital heraing loss 3) persons who have pace maker, cchlear implant, or other metal compatible with a contrindication of MRI

Design outcomes

Primary

Measure	Time frame
brain volume of extraauditory pathway bu MRIT1	—

Secondary

Measure	Time frame
speech discrimination, hearing level, HDSR, GDS, HHIE and blood findings (CRP, IL6, IL1b, TNFa, HDLC, LDLC, oxidative LDL, DHEAS, Cortisol, HbA1c, adiponectine)	—

Countries

Japan

Contacts

Public ContactMitsuhiro Aoki

Gifu University Hospital Department of Biomedical Informatics

aoki@gifu-u.ac.jp058-230-7292

Outcome results