The investigation of pathophysiology of migraine and mechanisms of acupuncture using Advanced-MRI. And the application for diagnosis.

The investigation of pathophysiology of migraine and mechanisms of acupuncture using Advanced-MRI. And the application for diagnosis. - The investigation of pathophysiology of migraine and mechanisms of acupuncture using Advanced-MRI

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000028222

Enrollment

Registered

2017-07-14

Start date

2017-07-07

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Migraine without aura

Interventions

Acupuncture once a week for 3 months. Healthy control

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Subjects must satisfy the following conditions for inclusion 1.Migraine without aura 2.Understand the explanation of the experiment and express consent.

Exclusion criteria

Exclusion criteria: 1. Neurological deficit and/or intracranial abnormality. 2. Having acupuncture therapy now 3. Pregnant 4. Perticipating another clinical trials"

Design outcomes

Primary

Measure	Time frame
Headache Impact Test (HIT-6): initials and 3 months later.	—

Secondary

Measure	Time frame
Numerical rating scale (NRS) Short-form 36 (SF-36) Self-rating depression scale (SDS) Neurite Orientation Dispersion and Density Imaging (NODDI) Resting state functional MRI (rsfMRI)	—

Countries

Japan

Contacts

Public ContactSumire Ishiyama

University of Tsukuba Graduate School of Comprehensive Human Sciences, Doctoral Program in Clinical Sciences

ckckck_sumire@yahoo.co.jp029-231-2371

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026