We intend for ASA PS 1-2 from 20-80years old having anoperation of limbs among orthopedics patients
Conditions
Interventions
Study group: 60 mg of sustained-release morphine sulfate administered orally at 90 to 120 minutes before introduction of general anesthesia. Then I went to the operating room. General anesthesia is
Sponsors
Tokyo women's medical university medical hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with good overall condition of 1-2 at ASA ps and cooperative patients for this survey were targeted. Also, in the survey group, those who got an understanding of this research before the surgery and gave the consent form were targeted.
Exclusion criteria
Exclusion criteria: We excluded those less than ASA physical status and non-cooperative in research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative pain and side effects for oral tablet morphine sulfate are mainly determined around 4-6,18-24 hours after oral. For postoperative pain relief, use of analgesic drugs as a main index.And we also visited patients up to 3 days postoperatively, including confirmation of side effects. | — |
Secondary
| Measure | Time frame |
|---|---|
| Key secondary outcomes for postoperativepain,and sedation :Postoperativepain are determined VAS scale, and diverted part of face scale. For sedation, use the Ramsay sedation score (RSS). In addition, measure the blood concentration at the perioperative period from some patients, and use it as a reference index of the drug effect. | — |
Countries
Japan
Contacts
Public ContactTakaaki Chino
Tokyo Women's medical University Medical Hospital Anestheology
Outcome results
None listed