Effect on the Tear Film Lipid Layer after Liposomal Spray in the Dry Eyes with Meibomian Gland Dysfunction

Effect on the Tear Film Lipid Layer after Liposomal Spray in the Dry Eyes with Meibomian Gland Dysfunction - Liposomal Spray and Tear Film Lpid Layer

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000028179

Enrollment

Registered

2017-08-21

Start date

2017-08-21

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dry eyes with meibomian gland dysfuncion

Interventions

Single application of liposomal spray Single application of normal saline

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients diagnosed as dry eye by 2006 diagnostic criteria Patients diagnosed as MGD by 2010 diagnostic criteria Tear film lipid layer thickness is less than 75nm by LipiView

Exclusion criteria

Exclusion criteria: Subjects without written informed consent Obvious ocular surface or eyelid disease Contact lens wear Punctal plug insertion

Design outcomes

Primary

Measure	Time frame
Time course of lipid layer thickness after liposomal spray application	—

Secondary

Measure	Time frame
Tear interferometric pattern Non invasive tear film breakup time Tear meniscus height Blink rate Subjective Symptoms	—

Countries

Japan

Contacts

Public ContactReiko Arita

Itoh Clinic Ophthalmology

ritoh@za2.so-net.ne.jp048-686-5588

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026