CAN we converT to tofogliflozin hydrate instead of diuretic AnTi-hypeRtensive medicine In type 2 diabetiC patiEnts associated with hypertension?

CAN we converT to tofogliflozin hydrate instead of diuretic AnTi-hypeRtensive medicine In type 2 diabetiC patiEnts associated with hypertension? - CANTATRICE Study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000028158

Enrollment

Registered

2017-07-10

Start date

2017-07-10

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension associated with type 2 diabetic mellitus

Interventions

Prescription of tofogliflozin instead of anti-hypertensive diuretics

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Poor controlled patients of type 2 diabetic mellitus who are taking antihypertensive diuretics including combined medicines with diuretics , and also to be considered reasonable and proper for prescription of SGLT3 inhibitors. Among these patients treating with oral diabetic medicines and in follow-up patients include.

Exclusion criteria

Exclusion criteria: Patients who are pregnant or possibility of pregnancy, uncontrolled blood pressure, over 80 yrs old, frailty, hypersensitivity of SGLT2 inhibitor, shows over 1000 U of AST or ALT, less than 45ml/min/1.73m2 of eGFR, or who are inadequate judged by physician.

Design outcomes

Primary

Measure	Time frame
Blood pressure	—

Secondary

Measure	Time frame
pulse rate	—

Countries

Japan

Contacts

Public ContactTakuma katsumata

Kanagawa Association of Medical and Dental Practitioners Department of Clinical Research

Katsumata.t@doc-net.or.jp045-313-2111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026