A study of the relationship between postoperative delirium and inflammatory markers.

A study of the relationship between postoperative delirium and inflammatory markers. - Postoperative delirium and inflammatory markers

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000028157

Enrollment

100

Registered

2017-07-10

Start date

2017-07-12

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative delirium

Interventions

Yokukansan group take 2.5 g of yokukansan before every meal from the morning of the previous day until the morning of the operation day. After surgery, patients start taking yokukansan as soon as poss

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The man and woman who agrees to the participation of the study named "Evaluation of the efficacy of yokukansan for postoperative delirium".

Exclusion criteria

Exclusion criteria: None.

Design outcomes

Primary

Measure	Time frame
The relationship between the presence/severity of delirium and inflammatory markers (NLRP3, IL-1beta, IL-6, IL-8, IL-18, TNF -alpha in serum or mononuclear leukocyte), and the effects of yokukansan.	—

Secondary

Measure	Time frame
Correlation between the inflammatory markers Association between safety, harmful phenomenon and inflammatory markers	—

Countries

Japan

Contacts

Public ContactIwata Masaaki

Tottori University Hospital Division of Neuropsychiatry

yanmasa@f8.dion.ne.jp0859-38-6547

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026