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Exploratory trial on the carry-over effect, accumulation effect and safety of long-term noisy galvanic vestibular stimulation on improvement of body balance in patients with bilateral vestibulopathy

Exploratory trial on the carry-over effect, accumulation effect and safety of long-term noisy galvanic vestibular stimulation on improvement of body balance in patients with bilateral vestibulopathy - Trial on the effect of long noisy galvanic vestibular stimulation in bilateral vestibulopathy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000028054
Enrollment
13
Registered
2017-07-05
Start date
2016-10-11
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

bilateral vestibulopathy

Interventions

To determine the optimal stimulus intensity of noisy GVS (0 - 1000 microA) using a stabilomenter. To apply noisy GVS with the optimal intensity for each patient, and evaluate postural stability and g

Sponsors

University of Tokyo Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients who showed corrective saccades to horizontal head impulses bilaterally, and showed reduced or absent caloric responses to ice water irrigation of the external auditory canal bilaterally (maximum slow phase eye velocity<10 deg/sec)

Exclusion criteria

Exclusion criteria: 1)Metal in the body, including intracephalic aneurysm clips and pace makers 2)Orthopedic disease 3)Heart disease 4)Inability to walk without assistance 5)A malignant tumor 6)Medicated by any tranquilizers and/or antidepressants 7)Consumed alcohol after 10 PM the day prior to the trial 8) Deemed not eligible by the investigator (co-investigator)

Design outcomes

Primary

MeasureTime frame
1. Changes in total length of the center of pressure (COP) from the baseline (From 0 to 3 h after the cessation of noisy galvanic vestibular stimulation) 2. Adverse events and troubles

Secondary

MeasureTime frame
1. Changes in envelopment area and root meas square (RMS) of COP from the baseline 2. Changes in gait velocity, step length and step time

Countries

Japan

Contacts

Public ContactShinichi Iwasaki

University of Tokyo Hospital

iwashin-tky@umin.ac.jp0358008665

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026