Patients without diabetes mellitus who were received surgical operation including esophagectomy, gastrectomy, hepatectomy and pancreatectomy
Conditions
Interventions
Perioperative glycemic control using artificial pancreas is performed to be targeting blood glucose ranging from 80 to 110 mg/dL during 2 days.
Perioperative glycemic control using artificial pancreas
Sponsors
Kochi Medical School
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients who undergo esophagectomy, gastrectomy, hepatectomy and pancreatectomy. 2. Patients without diabetes mellitus whose Hemoglobine A1c is 6.4% or below. 3. A performance status of 0-2 accord ing to the Eastern Cooperative Oncol ogy Group (ECOG) scale. 4. An age of 20 years and over. 5. Patients who are considered to survive for more than 3 months from the registration. 6. Vital organ functions are preserved within 14 days prior to entry. 7. Sufficient oral intake. 8. All patients gave written informed consent.
Exclusion criteria
Exclusion criteria: 1. Obvious infection or inflammation. 2. Serious cardiovascular diseases. 3. Serious concurrent disease such as intestinal palsy, small bowel obstraction, uncontrolable diabetes mellitus, renal failure, liver cirrhosis, and so on. 4. Massive ascites beyond the pelvic cavity or pleural effusion. 5. Women who are pregnant or hope to become pregnant during the study period. Men who wish their partner to become pregnant. 6. Patients judged inappropriate for the study by their physicians.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum IL-6 levels on on postoperative 3. | — |
Secondary
| Measure | Time frame |
|---|---|
| Morbidities including surgical Site Infection, mortality, hospitalization days, IL-6 at postoperative day 1, and CRP at postoperative day 3. | — |
Countries
Japan
Contacts
Public ContactTsutomu Namikawa
Kochi Medical School Department of Surgery
Outcome results
None listed