Assessment of treatment area by transcatheter arterial chemoembolization under administration of SPIO using MRI

Assessment of treatment area by transcatheter arterial chemoembolization under administration of SPIO using MRI - Assessment of treatment area by transcatheter arterial chemoembolization under administration of SPIO using MRI

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000028032

Enrollment

Registered

2017-09-01

Start date

2017-09-28

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatocellular carcinoma

Interventions

MRI scan under administration of SPIO before transcatheter arterial chemoembolization. MRI scan 3 to 5 days after the transcatheter arterial chemoembolization

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)Diagnosis of hepatocellular carcinoma according to EASL guideline 2)Chemoembolization is indicated. 3)Performance status of 0-2 4)Liver function of Child-pugh A or B 5)eGFR is 30mL/min/1.73m2 or more 6)Platelet count of 50,000 microL or more 7)No previous treatment or 4 weeks after the previous treatment 8)Informed consent is obtained.

Exclusion criteria

Exclusion criteria: 1)Rupture of hepatocellular carcinoma 2)History of surgical or endoscopic treatment of bile duct 3)Prominent arterioportal or arteriovenous shunts 4)Dissection or stenosis of 50% or more in the celiac trunk or hepatic artery 5)Hepatic coma or severe psychiatric disorder 6)Severe drug allergy including SPIO or iodine contast allergy 7)Inadequate patients to undergo the procedure safely

Design outcomes

Primary

Measure	Time frame
local recurrence	—

Countries

Japan

Contacts

Public ContactSodai Hoshiai

Faculty of Medicine, University of Tsukuba Department of Radiology

hoshiai@md.tsukuba.ac.jp0298533205

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026