Comparison between using PMMA and AN69ST membrane hemofilter in Continuous hemodiafiltration (CPAC study)

Comparison between using PMMA and AN69ST membrane hemofilter in Continuous hemodiafiltration (CPAC study) - Comparison between using PMMA and AN69ST membrane hemofilter in Continuous hemodiafiltration (CPAC study)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000028025

Enrollment

100

Registered

2017-07-01

Start date

2017-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

burn, severe acute pancreatitis, sepsis

Interventions

Continuous hemodiafiltration using PMMA membrane hemofilter Continuous hemodiafiltration using AN69ST membrane hemofilter

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: ->=20 years of age -Able and willing to provide informed consent -Patients with burn, severe acute pancreatitis or sepsis -Patients with KDIGO stage 1 screened -Patients who require continuous hemodiafiltration for more than 24 hours

Exclusion criteria

Exclusion criteria: -Pregnant women -Patients with chronic kidney disease or who received RRT before randomization -Patients with terminal cancer -Patients with body weight less than 30 kg -Patients considered ineligible for the study by the investigator

Design outcomes

Primary

Measure	Time frame
-Changes of scores (SOFA, SAPS2, APACHE2, DIC score, CAI) at 48 and 72 hours after enrollment	—

Secondary

Measure	Time frame
-Duration of mechanical ventilation in 28 days -Survival rate at 90 days -ICU stay days -Hospital stay days -Changes of plasma lactate and IL-6 level at 72 hours after continuous hemodiafiltration -Filter lifetime -Total fluid volume	—

Countries

Japan

Contacts

Public ContactRyota Sakurai

Faculty of Medicine, Saga University Department of Emergency and Critical Care Medicine

sr0737@cc.saga-u.ac.jp0952-31-6511

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026