Correlation between radiation doses and salivary gland function preservation associated with radiotherapy for patients with head and neck cancer using salivary gland scintigraphy

Correlation between radiation doses and salivary gland function preservation associated with radiotherapy for patients with head and neck cancer using salivary gland scintigraphy - Correlation between radiation dose and salivary gland secretion associated with radiotherapy

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000028021

Enrollment

Registered

2017-07-01

Start date

2017-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

head and neck cancer

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Pathologically proven as head and neck cancer patients over 20 years of age. 2) Patients with preserved salivary gland functions 3) Patient with Performance Status of 0-1. 4) Patients without autoimmune diseases, such as Sjogren's syndrome 5) Patients who are able to provide written informed consents

Exclusion criteria

Exclusion criteria: 1) Prognosis is expected to be less than 6 months 2) Suffering from severe underlying diseases, such as liver cirrhosis, diabetes mellitus and heart diseases 3) Suffering from severe allergic reactions to drugs 4) Pregnant or breast-feeding women, or women who may become or want to become pregnant in the near future 5) No previous history of receiving whole neck radiotherapy

Design outcomes

Primary

Measure	Time frame
To assess the scores of salivary gland secretion amounts and recovery rates by the salivary gland scintigraphy before and after radiotherapy	—

Countries

Japan

Contacts

Public ContactTomohiro Itonaga

Tokyo Medical University Department of radiology

itonaga@tokyo-med.ac.jp0333426111

Outcome results