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Unraveling the pathogenesis and relationship among manometric subtype of esophageal achalasia and achalasia-related disease, using cytokine profile expressed in the muscle layer

Unraveling the pathogenesis and relationship among manometric subtype of esophageal achalasia and achalasia-related disease, using cytokine profile expressed in the muscle layer - Unraveling the pathogenesis and relationship among manometric subtype of esophageal achalasia using cytokine profile expressed in the muscle layer

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000028004
Enrollment
120
Registered
2017-06-29
Start date
2017-04-10
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal achalasia

Interventions

None listed

Sponsors

Department of Medicine and Bioregulatory, Graduate School of Medical Sciences, Kyushu University
Lead Sponsor
Digestive Disease Center, Showa University koto Toyosu Hospital
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients with esophageal achalasia and achalasia-related disease Patients who are aged 20 years or older at the time of acquisition

Exclusion criteria

Exclusion criteria: Patients who reject this research

Design outcomes

Primary

MeasureTime frame
The expression of cytokine and transcription factor related to Th1/Th2/Th17 immunological response in esophageal achalasia and achalasia-related disease

Secondary

MeasureTime frame
The relationship between achalasia subtype and the pattern of cytokine expression in esophageal muscle layer The relationship between achalasia subtype and the esophageal / intestinel flora Pathological diference among esophageal achalasia subtype

Countries

Japan

Contacts

Public ContactEikichi Ihara, Koji Mukai

Graduate school of Medical Sciences, Kyushu University Department of Medicine and Bioregulatory

eikichi@intmed3.med.kyushu-u.ac.jp092-642-5286

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026